Nano Biomedicine

Fabrication Methods of Hydroxyapatite Nanocomposites

Masahiro OKADA, and Takuya MATSUMOTO
Department of Biomaterials, Graduate School of Medicine,
Dentistry and Pharmaceutical Sciences,
Okayama University, Okayama, Japan

Nano Biomed 2016;8(1): 15-26, (June 30, Nano Biomedicine)

Artificially synthesized hydroxyapatite (HAp) exhibits excellent biocompatibility with various kinds of cells and tissues, making it an ideal candidate for orthopedic and dental applications. HAp-based nanocomposites with polymers, metals, and other kinds of bioceramics have developed in order to improve the mechanical strength of HAp. This review is focused on providing a summary of existing knowledge and recent advances on fabrication methods of HAp nanocomposites.

Key words: hydroxyapatite, nanoparticle, nanocomposite, fabrication method, medical device

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