Nano Biomedicine
REVIEW ARTICLE

Fabrication Methods of Hydroxyapatite Nanocomposites

Masahiro OKADA, and Takuya MATSUMOTO
Department of Biomaterials, Graduate School of Medicine,
Dentistry and Pharmaceutical Sciences,
Okayama University, Okayama, Japan


Nano Biomed 2016;8(1): 15-26, (June 30, Nano Biomedicine)

Synopsis
Artificially synthesized hydroxyapatite (HAp) exhibits excellent biocompatibility with various kinds of cells and tissues, making it an ideal candidate for orthopedic and dental applications. HAp-based nanocomposites with polymers, metals, and other kinds of bioceramics have developed in order to improve the mechanical strength of HAp. This review is focused on providing a summary of existing knowledge and recent advances on fabrication methods of HAp nanocomposites.

Key words: hydroxyapatite, nanoparticle, nanocomposite, fabrication method, medical device

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