Nano Biomedicine

Porous Hydroxyapatite Can Improve Strength and Bioactive Functions of Glass Ionomer Cement

Takako NISHIMURA1, Yukari SHINONAGA2, Yoko ABE2, Saki KAWAI2, and Kenji ARITA2
1Graduate School of Dentistry (Department of Pediatric Dentistry), Osaka Dental University,
2Department of Pediatric Dentistry, Osaka Dental University, Osaka, Japan

Nano Biomed 2014;6(2): 53-62, (Dec 30)

The aim of this study is to investigate the role of hydroxyapatite (HAp) in novel apatite ionomer cement (AIC), an improved glass ionomer cement (GIC) that contains porous HAp. AIC samples were prepared using the latest conventional GIC, Fuji IX GP ExtraTM, with porous and spherical HAp (HApS), and were subjected to mechanical strength measurements, fluoride release test, scanning electron microscopy observations and multi-mineral release test, and were compared with IX-Ex, Fuji IX GPTM(IX-GP) and S-PRG filler containing composite resin, Beautifil IITM (GIOMER). The flexural strength and fluoride release properties of AIC were significantly higher than those of IX-Ex. The release of fluoride, aluminum, silicon and phosphorus from AIC specimens was greater when compared with IX-Ex and GIOMER. Therefore, porous HAp improves both the strength and bioactive functions of GIC without losing the advantages of conventional GIC.

Key words: glass ionomer cement, hydroxyapatite, ion release, bioactive functions

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