Nano Biomedicine
ORIGINAL ARTICLE

Antithrombogenicity of Amorphous Deuterated Carbon Film Prepared by RF-plasma CVD

 Kazuhide OZEKI1, Daiichiro SEKIBA2, Kenji K. HRAKURI3, and Toru MASUZAWA1

 1Department of Mechanical Engineering, Ibaraki University, Ibaraki, Japan
2Inst. of Applied Physics, University of Tsukuba, Ibaraki, Japan
3Department of Electronic & Computer Engineering, Tokyo Denki University, Tokyo, Japan
Nano Biomed 2013;5(1):11-17, (Jun 30)
Synopsis
Amorphous hydrogenated carbon (a-C:H) and amorphous deuterated carbon (a-C:D) films were prepared using radio frequency plasma-enhanced chemical vapor deposition (RF-PECVD) from CH4 and CD4 gas sources, respectively. Both films were prepared by adjusting the process pressure between 1 and 300 Pa. The films were characterized using Raman spectroscopy, and the concentrations of hydrogen (H) and deuterium (D) relative to carbon (C) in the films were determined by elastic recoil detection analysis (ERDA) and Rutherford backscattering spectroscopy (RBS).
Contact angle and blood clot formation on the films were observed to evaluate the antithrombogenicity of the a-C:H and the a-C:D films. The a-C:D film contact angles were lower than the a-C:H film contact angles. These lower contact angles were correlated to lower antithrombogenicity of the a-C:D films compared with the a-C:H films.

Key words: amorphous hydrogenated carbon, deuterium, hydrogen, antithrombogenicity, contact angle

"Nano Biomedicine" Homepage(English)

"Nano Biomedicine" Homepage(Japanese)