Sex Differences in Susceptibility to Nanomaterials
Gaku ICHIHARA1, Cai ZONG1, Mamiko TAKISADA1,
Kyoka YAMAZAKI1, Shiho MURAKI1, and Sahoko ICHIHARA2 1Department of Occupational and Environmental Health, Faculty of Pharmaceutical Sciences,
Tokyo University of Science, Noda, Japan 2Department of Environmental and Preventive Medicine, Jichi Medical University School of Medicine, Shimotsuke, Japan
Synopsis Experimental and epidemiological studies suggested sex difference in susceptibility to manufactured nanomaterials and conventional fibrous materials. Sex hormone, nuclear factor erythroid 2-related factor (NFE2L2, Nrf2) and other unknow factors should be investigated to understand the mechanism of sex difference in susceptibility.