Many types of metal nanoparticles (NPs) are increasingly available for use as dental materials. The study evaluated the biofilm-growth inhibitory effects of silver NPs (AgNPs) and platinum NPs (PtNPs) against Streptococcus mutans
). Two types of NPs, stabilized by polyvinylpyrrolidone (PVP), which has a negative surface charge, were used in this study. This study evaluated the effects of specific NPs, having two different core-metal compositions (Ag and Pt) and an identical surface-capping agent (PVP), on the disruption of initial biofilm growth. This was achieved using a biofilm-forming assay, and micromorphological examinations using a transmission electron microscope. The PtNPs inhibited a biofilm growth against S. mutans
; however, no inhibitory effect was found in the case of the AgNPs. It was observed that the PtNPs adhered to the bacteria surface; however, no adhesion was observed in the case of the AgNPs. We speculate that the attachment of the NPs to S. mutans has an inhibitory effect on the biofilm formation during growth.
Key words: nanoparticle, capping agent, Streptococcus mutans, biofilm
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